Class: Ryanodine_Receptor

•owl:Thing
        •bfo:Entity
                •snap:Continuant
                        •snap:IndependentContinuant
                                •snap:Object
                                        •Molecule
                                                •Protein
                                                        •Ion_Channel
                                                                •Calcium_Channel
                                                                        •Intracellular_Calcium_Channel
                                                                                •Ryanodine_Receptor

Super Classes

Intracellular_Calcium_Channel

Annotations

birn_annot:curationStatusuncurated
definitionProtein complexes that mediate the release of calcium from the sarcoplasmic reticulum in both skeletal and cardiac muscle cells by forming tetrametric complexes. These complexes each then act as a calcium channel. There are three isoforms of the RyR: RyR1, RyR2, and RyR3. RyR1 is specifically expressed in skeletal muscles and RyR2 in cardiac muscles. RyR3 is yet another isoform found in non-muscle cells such as neuronal cells. (From Yonsei Med J 1996;37(1):72-80) (MSH)
sao_IDsao960745141
umls_IDC0054493
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