Class: Synapse


Super Classes

has_Aggregate_Part ONLY (Post-synaptic_Density AND Vesicle AND Junction_Complex)
intercellular_Junction_Compartment SOME Chemical_Synapse_Type
located_in ONLY Synaptic_Site


definitionThe junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane (Gene Ontology).


Class Description/Definition (Necessary Conditions)

Chemical_Synapse, Electrotonic_Synapse, Mixed_Synapse
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