Class: AMPA_Receptor

•owl:Thing
        •bfo:Entity
                •snap:Continuant
                        •snap:IndependentContinuant
                                •snap:Object
                                        •Molecule
                                                •Protein
                                                        •Membrane_Receptor
                                                                •Neurotransmitter_Receptor
                                                                        •Glutamate_Receptor
                                                                                •AMPA_Receptor

Super Classes

Glutamate_Receptor

Disjoint Classes

NMDA_Receptor

Annotations

birn_annot:curationStatusuncurated
definitionCell surface proteins that bind glutamate and directly gate ion channels in cell membranes. AMPA receptors were originally discriminated from other glutamate receptors by their affinity for the agonist AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid). They are probably the most common mediators of fast excitatory synaptic transmission in the central nervous system. Several subtypes have been cloned, and for some types the traditional distinction from kainate receptors may not apply (MSH).
sao_IDsao265434492
umls_IDC0072899

Usage

Class Description/Definition (Necessary Conditions)

GluR1, GluR2, GlurR3
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