Figure 392 from Chapter 15 (Cytoplasmic Inclusions) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. Frog neuromuscular junction, prepared by rapid freezing with liquid helium followed by freeze substition. The nerve terminal is wrapped by a myelinating Schwann cell, and is separated from the postsynaptic surface of the muscle by the synaptic cleft which contains an external lamina. Image by John Heuser and Tom Reese. A PDF copy of the accompanying chapter is available on the ASCB’s BioEDUCATE website.