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CIL:39029*  Cite 

Confocal micrograph of a blind cavefish embryo at around five days post-fertilisation viewed from the side (lateral view) with an antibody that targets a calcium binding protein (calretinin) shown in green, which highlights different neuronal types and their processes in the nervous system. The cavefish Mexican tetra (Astyanax mexicanus) has a seeing and a blind form; the latter lives in dark environments, and relies on other senses. The blind cavefish has specially adapted traits that its sighted relation (dwelling near the surface) does not. These include a greater number of sensory receptors and taste buds along its body; these taste buds are also more efficient than the equivalent cells in the seeing cavefish. The eyes are still present at this stage of development but they will degenerate naturally during the lifetime of the fish as they live in a dark environment where eyes are redundant. Adult cavefish are blind.

Technical Details

B0007769 Cavefish embryo. Wellcome Images available under the following creative commons usage

Biological Sources
NCBI Organism Classification
Astyanax mexicanus
Cell Type
Cellular Component
neuron projection
neuronal cell body
Biological Context
Biological Process
neuron remodeling
Monica Folgueira
Steve Wilson
Wellcome Images
Digital Object Identifier (DOI)
Archival Resource Key (ARK)
Image Type
recorded image
Image Mode
confocal microscopy
Parameters Imaged
fluorescence emission
Source of Contrast
distribution of epitope
Visualization Methods
primary antibody plus labeled secondary antibody
Processing History
unprocessed raw data
Sample Preparation
chemically fixed tissue
Relation To Intact Cell
whole mounted tissue
Spatial Axis Image Size Pixel Size
X 800px ——
Y 485px ——