Transmission electron micrograph of a thin section of the nucleus of a HeLa cell with mutant ALADIN. This grazing section of the nucleus shows en face views of nuclear pores which appear to have a normal ultrastructure. From a study of the role of the nuclear porin ALADIN. Other images in this group show further details of nuclear pore structure in normal and mutant cells.
Normal HeLa cells expressing were fixed with glutaraldehyde, embedded in epoxy resin, thin sectioned, and imaged using a Philips CM10 TEM. See: J Cronshaw and M Matunis 2003 The nuclear pore complex ALADIN is mislocalized in triple A syndrome Proc Natl Acad Sci USA 100 5823-5827
|Spatial Axis||Image Size||Pixel Size|