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CIL:41732*  Cite 

Confocal micrograph showing a dividing cancer cell (HeLa) in time-lapse. Cellular structures have been visualised in cyan (cell membrane) and red (DNA). The spiral arrangement captures the journey of a cell as it divides and creates new cells. HeLa cells undergo cell division approximately once every 16 hours. The cell spends a substantial portion of this time preparing itself for division during interphase, and the actual process by which the cell physically divides takes approximately an hour. The cell in the center of the image has completed prophase and pro-metaphase by rounding and aligning its duplicated DNA in the center (metaphase). It is now ready to pull the identical copies of DNA to opposing ends of the cell (anaphase, approximately eight minutes). This is followed by cytokinesis (approximately 15-20 minutes), when the cell contraction in the middle and physically separates into two daughter cells. Wellcome Image Award 2012.

Technical Details

B0008488 . 2011 Collection: Wellcome Images Copyrighted work available under Creative Commons by-nc-nd 2.0 UK: England & Wales, see

Biological Sources
NCBI Organism Classification
Homo sapiens
Cell Line
Cellular Component
plasma membrane
condensed chromosome
Kuan-Chung Su
Mark Petronczki
Wellcome Images
London Research Institute, Cancer Research, UK
Digital Object Identifier (DOI)
Archival Resource Key (ARK)
Image Type
recorded image
Image Mode
time lapse microscopy
confocal microscopy
Parameters Imaged
fluorescence emission
Source of Contrast
distribution of epitope
Processing History
montage created from time lapse data
Sample Preparation
living tissue
Relation To Intact Cell
dispersed cells in vitro
Spatial Axis Image Size Pixel Size
X 444px ——
Y 550px ——