Alternate header for print version


Image 2D
Display image description
Electron micrograph of the cell body of a 0.25 um thick section through a cortical pyramidal neuron from the brain of a patient with Alzheimer's disease. The specimen was prepared from biopsy material obtained several decades ago.
Full resolution image description
Stack of serial section electron micrographs in IMOD st format produced using the IMOD Newstack function.

License
Attribution Only: This image is licensed under a Creative Commons Attribution License. View License Deed | View Legal Code

CCDB:6355*
Project: P1700
Project name
Alzheimer neuron reconstructions
Description
Reconstruction of cortical neurons from biopsy material obtained from Alzheimers disease patients
Funding agency
National Institutes of Health
Leader(s)
Mark Ellisman
Collaborator(s)
Rama Ranganathan
Thomas J. Deerinck
Stephen J. Young
David Hessler
and Robert D. Terry
Start date
unspecified
End date
unspecified
 
Experiment
Experiment ID
3448
Experiment date
01-01-1987
Title
Alzheimer reconstruction
Purpose
Reconstruction of Alzheimers neurons using serial section EM
Experimenter(s)
Tom Deerinck
Microscopy product
Microscopy product ID
6355
Instrument
JEOL 100CX
Microscopy type
TEM
Product type
SERIAL SECTION
Image basename
ALZ_3486
Spatial Axis Image Size Pixel Size
X 4912px
Y 6338px
Subject
Species
human
Scientific name
homo sapiens
Strain
sapiens
Group by
disease status
Treatment
patients diagnosed with Alzheimers disease
Age class
aged
Tissue section
Anatomical location
cerebral cortex
Microtome
ultramicrotome
Thickness
0.25 µm
Specimen description
Organ
brain
System
central nervous system
Cell type
Neocortex pyramidal cell
Imaging parameters
Type
Electron microscopy product
Recording medium
film
Magification
3300
Accelerating voltage
100 KeV
Imaging product type
Type
Serial section
Description
Alzheimer Neuron
Z resolution
0.25 µm