Spontaneous symmetry breaking and motility initiation of keratocytes. Phase-contrast time-lapse video of a keratocyte spontaneously breaking symmetry and initiating motility. The cell has been reorien...

Spontaneous symmetry breaking and motility initiation of keratocytes. Phase-contrast time-lapse video of a keratocyte spontaneously breaking symmetry and initiating motility. The cell has been reorien...

Smooth, Canoe-Shaped Keratocytes Migrate "Coherently", with Fast Speeds and Persistent Shapes, whereas Rough, D-Shaped Keratocytes Migrate "Decoherently", with Slower Speeds and Fluctuating Shapes Smo...

Local application of calyculin A (phosphatase inhibitor) can stimulate motility initiation. Phase-contrast time-lapse video of a stationary keratocyte exposed to a local application of calyculin A. Re...

Nascent Lamellipodia Emerge with Rough Edges and Rapidly Acquire a Smooth Morphology. A glass micropipette, acting as a barrier, was lowered into the path of movement of a migrating, coherent keratocy...

Formation of an actin axle during the maturation of polarity. During maturation of the polarized form, the circular actin bands around the cell body transitioned to an actin axle along the cell rear. ...

Visualization of F-actin network movement in stationary keratocytes with FSM. F-actin flows centripetally from the cell periphery to the cell body in stationary cells. Video shows paired phase-cont...

Visualization of F-actin network movement in motile keratocytes with FSM. F-actin flows slowly from the leading edge to the cell body in motile cells. Video is paired phase-contrast and AF546-phallo...