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Summary Information Microscopy product ID: 3632 Image basename: CTL_ImmunSynapse Summary Project ID P1694 Leader Stephen Fuller, Endre Majorovits  (Other projects) Collaborators Gillian Griffiths, Jane Stinchcombe, Giovanna Bossi Project Description Tomogram of the immunological synapse between a human cytotoxic T lymphocyte (CTL) and a target cell Experiment Purpose Defining the structure of the immunological synapse between a human cytotoxic T lymphocyte (CTL) and a target cell and assessing the rearrangement of the microtubule organization center (MTOC) and attached organelles within the CTL during target killing. Species Human System blood Organ blood Region Cell type Cytotoxic T Lymphocyte Structure CTL immunological synapse Product Type DOUBLE TILT Instrument FEI Tecnai F30 Publications Jane C. Stinchcombe, Endre Majorovits, Giovanna Bossi, Stephen Fuller, Gillian M. Griffiths. Centrosome polarization delivers secretory granules to the immunological synapse. Nature 443 (2006) 462-465 View all details

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